Lung Cancer Research
Ongoing research on biomarkers, molecular profiling, and immune landscape of non-small cell lung cancer (NSCLC) in northeastern Brazil, including PD-L1, ALK, EGFR, and GSK-3β.
Since 2012, our group at the Federal University of Ceará Graduate Program in Pathology has conducted a series of prospective and retrospective studies on lung cancer biomarkers and outcomes.
Active research lines:
- PD-L1 expression and its association with EML4-ALK and EGFR status in pulmonary adenocarcinomas from northeastern Brazil
- GSK-3β expression as a prognostic biomarker in resected NSCLC
- Immunohistochemical profiling of dendritic cells in mediastinal lymph nodes of NSCLC patients
- Impact of lymphadenectomy adequacy on survival after lung resection
- DLL3, ASC1, TTF-1 and Ki-67 co-expression in small cell lung cancer
- Patterns of oncologic care and molecular testing access in a public hospital setting
Selected publications:
- Silva et al., Oncotarget 2024
- Alves et al., Frontiers in Oncology 2021
- Oliveira et al., J Bras Pneumol 2019
- Torres et al., Analytical Cellular Pathology 2014